I vaguely recall an interview where she said the casting team weren't aware of her previous link to the character. That said, it's become a kind of tradition in the various Superman movies and tv series:
Noel Neill (Lois in the 1940s show) played Lois' mother Ella in the 1978 movie (uncredited, but she and Lois are the mom and child on the train the young Clark runs past), and had a cameo in the 2006 reboot.
Phyllis Coates (Lois in the 1951 movie) turned up as Lois' mom Ellen in a 1994 episode of The New Adventures of Superman. 'Her' Superman, Kirk Alyn, played a general in the 1978 movie.
Dean Cain, the 1990s Kal-El, played a villain in Smallville, whilst 'his' Lois, Teri Hatcher, played Ella Lane.
As well as Ms O'Toole, Smallville also featured Terence Stamp (Zod) as the voice of Jor-El, Chrstopher Reeve (Kal-El) as a mysterious scientist and Margot Kidder (Lois) as his assistant.
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Noel Neill (Lois in the 1940s show) played Lois' mother Ella in the 1978 movie (uncredited, but she and Lois are the mom and child on the train the young Clark runs past), and had a cameo in the 2006 reboot.
Phyllis Coates (Lois in the 1951 movie) turned up as Lois' mom Ellen in a 1994 episode of The New Adventures of Superman. 'Her' Superman, Kirk Alyn, played a general in the 1978 movie.
Dean Cain, the 1990s Kal-El, played a villain in Smallville, whilst 'his' Lois, Teri Hatcher, played Ella Lane.
As well as Ms O'Toole, Smallville also featured Terence Stamp (Zod) as the voice of Jor-El, Chrstopher Reeve (Kal-El) as a mysterious scientist and Margot Kidder (Lois) as his assistant.
Pretty sure that's all of them...